Multiple failures due to lack of efficacy and/or adverse events
Market focus is on F2-F4 patients.
NASH is highly complex disease that can cause a severely compromised lifestyle and even death – a targeted and multi-pronged approach is required for success.
The problems with these (current) therapies: “Several pathways are implicated to play a role in NASH pathophysiology from the progression of normal liver fat levels to steatohepatitis and, consequently, fibrosis of the liver.” (Global Market Data, 2020)